ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents in bark of Larix olgensis var. koreana.</p><p><b>METHOD</b>The compounds were isolated with silica gel column chromatography and their structures were elucidated on the basis of spectral analysis (IR, EI-MS, 1H-NMR, 13C-NMR).</p><p><b>RESULT</b>Eight compounds were isolated and identified as isopimaric acid (I), beta-sitosterol (II), 24R,5alpha-stigmast-3,6-dione (III), larixol (IV), ferulic acid (V), lariciresinol (VI), secroisolariciresinol (VII) and isolariciresinol (VIII).</p><p><b>CONCLUSION</b>All the compounds were isolated from this plant for the first time.</p>
Subject(s)
Carboxylic Acids , Chemistry , Furans , Chemistry , Larix , Chemistry , Lignans , Chemistry , Phenanthrenes , Chemistry , Plant Bark , Chemistry , Plants, Medicinal , Chemistry , Sitosterols , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of the bulbs of Bolbostemma panicultum.</p><p><b>METHOD</b>The compounds were isolated by column chromatography on silica gel, C18, Sephadex LH-20 separately and their structures were elucidated by chemical and spectroscopic technologies.</p><p><b>RESULT</b>Eight compounds were isolated and identified as maltol(I), emodin(II), cucurbitacin B(III), cucurbitacin E(IV), stigmasta-7, 22, 25-triene-3-ol(V), stigmasta-7, 22, 25-triene-3-nonadecanoic acid ester(VI), stigmasta-7, 22, 25-triene-3-O-beta-D-glucopyranoside(VII), stigmasta-7, 22, 25-triene-3-O-beta-D-(6'-palmitoyl) glucopyranoside(VIII).</p><p><b>CONCLUSION</b>I-VIII were obtained from this plant for the first time; VI and VIII are new compounds.</p>
Subject(s)
Cucurbitaceae , Chemistry , Emodin , Chemistry , Molecular Structure , Plant Roots , Chemistry , Plants, Medicinal , Chemistry , Saponins , Chemistry , Stigmasterol , Chemistry , Triterpenes , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To develop an HPLC method for determining flavoniod-glycosides in Yixintong pills.</p><p><b>METHOD</b>Agilent ZORBAX Extend-C18 (4.6 mm x 250 mm, 5 microm) was used with tetrahydrofuran-methanol-acetonitrile-water-acetic acid (30:3:4:120:3) as mobile phase. Detection wavelength was 330 nm.</p><p><b>RESULT</b>Good linearities of rhamnosylvitexin and vetexin-glucoside were obtained within the range of 0.044-1.78 microg (r = 0.9999) and 0.042-0.85 microg (r = 0.9999); the average recoveries were 100.0% and 99.2%; RSD were 0.92% and 1.8%, respectively.</p><p><b>CONCLUSION</b>This method can be used for quality control of Yixintong pills.</p>
Subject(s)
Apigenin , Chromatography, High Pressure Liquid , Crataegus , Chemistry , Drugs, Chinese Herbal , Chemistry , Plant Leaves , Chemistry , Plants, Medicinal , Chemistry , Quality ControlABSTRACT
<p><b>AIM</b>To study the lignans from Patrinia scabra Bunge.</p><p><b>METHODS</b>The constituents were separated and purified by column chromatography with silical gel, RP-silical gel and Sephadex LH-20. Their structures were identified on the basis of spectral data (IR, MS, 1HNMR, 13CNMR, HMQC and HMBC).</p><p><b>RESULTS AND CONCLUSION</b>A new lignan was obtained and its structure was elucidated as 4-[1-ethoxyl-1-(4-hydroxy-3-methoxy)benzyl]methyl- 2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyl-tetrahydro-furan (2), along with three known lignans, lariciresinol (1), isolariciresinol (3) and nortracheloside (4).</p>
Subject(s)
Furans , Chemistry , Guaiacol , Chemistry , Lignans , Chemistry , Lignin , Chemistry , Molecular Structure , Naphthols , Chemistry , Patrinia , Chemistry , Plant Roots , Chemistry , Plants, Medicinal , ChemistryABSTRACT
<p><b>AIM</b>To study the chemical constituents of Bletilla striata.</p><p><b>METHODS</b>Various column chromatographies with silica gel and Sephadex LH-20 were employed for the isolation and purification. The structures of the compounds were elucidated on the basis of spectral analyses and chemical methods.</p><p><b>RESULTS</b>Three compounds were isolated from the roots of Bletilla striata (Thunb.) Reichb. f. and identified as 5-hydroxy-4-(p-hydroxybenzyl)-3'-3-dimethoxybibenzyl (I), schizandrin (II), 4,4'-dimethoxy-(1,1'-biphenanthrene)-2,2',7,7'-tetrol (III).</p><p><b>CONCLUSION</b>Compound I is a new bibenzyl derivative and II was isolated from this plant for the first time.</p>